Intracranial Metastases

Intracranial metastases: therapeutic options.

Metastatic spread of tumour cells detached from systemic tumours into the central nervous system occurs hematogenously since lymphatic drainage is absent in the brain. Little is known about the precise mechanisms of tumour cell attachment in the brain and local progression of micrometastasis into clinically symptomatic tumours or into lesions visible on modern imaging techniques, such as magnet...

Remote metastases from intracranial tumours.

A review of the primary tumours of the nervous system encountered over the past 16 years from the population of the west of Scotland uncovered only three tumours in which remote extracranial metastases had developed. In all three, there had been surgical intervention before the appearance of metastases. The findings in these patients are compared with those in other published accounts of this u...

Vertebral metastases from intracranial meningioma

Meningioma rarely gives rise to metastases outside the brain and meninges. We report here a case of a patient who was treated for anaplastic brain meningioma with surgery and fractionated radiation therapy without any recurrence until 5 years after the operation, when she developed vertebral metastases.

Bone and lung metastases from intracranial meningioma.

Fifteen percent of intracranial tumors are represented by meningiomas. Meningioma is usually a benign neoplasm; malignant histology is rare and represents about 2-10% with a 43% incidence of metastasis. The most frequent site of metastasis is the lung and rare are other sites. There are no definitive criteria to predict the recurrence or metastases of meningioma and histological grading, accord...

Response of intracranial metastases to erlotinib therapy.